Hydroxide → HCID 67378537, compound

HRID 316335Notes

Reaction equation

HRID 316335 reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][cH:7][c:8]([CH2:11][NH:12][C:13](=[O:14])[CH:15]2[NH:16][CH:17]([CH2:38][C:39]([CH3:40])([CH3:41])[CH3:42])[C:18]([C:28]#[N:29])([c:30]3[c:31]([F:37])[cH:32][c:33]([Cl:36])[cH:34][cH:35]3)[CH:19]2[c:20]2[c:21]([F:27])[c:22]([Cl:26])[cH:23][cH:24][cH:25]2)[cH:9][cH:10]1.[Li+:45].[OH-:44].[OH2:43].[OH2:51]>>[O:2]=[C:3]([OH:4])[c:5]1[n:6][cH:7][c:8]([CH2:11][NH:12][C:13](=[O:14])[CH:15]2[NH:16][CH:17]([CH2:38][C:39]([CH3:40])([CH3:41])[CH3:42])[C:18]([C:28]#[N:29])([c:30]3[c:31]([F:37])[cH:32][c:33]([Cl:36])[cH:34][cH:35]3)[CH:19]2[c:20]2[c:21]([F:27])[c:22]([Cl:26])[cH:23][cH:24][cH:25]2)[cH:9][cH:10]1

Participants

6

Reactant 5

HCID 961HydroxideHCID 962Water2×HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 67378506Methyl 5-[[[3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]methyl]pyridine-2-carboxylate

Product 1

HCID 67378537HCID 67378537, compound

Sources & evidence

ORD record
ord-4aceefdf07cc47e59d00e7a9a9bc3b3b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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