Ethyl Acetoacetate → 2-(2-Methyl-1,3-dioxan-2-yl)ethanol

HRID 31639Notes

Reaction equation

[CH2:1]([C:4]1([CH2:10][CH2:11][OH:12])[O:9][CH2:8][CH2:7][CH2:6][O:5]1)CC.C(OCC)(=O)CC(C)=O>>[CH3:1][C:4]1([CH2:10][CH2:11][OH:12])[O:9][CH2:8][CH2:7][CH2:6][O:5]1

Participants

Reactant 2

HCID 8868Ethyl Acetoacetate

HCID 597924352-(2-Propyl-1,3-dioxan-2-yl)ethanol

Product 1

HCID 596567682-(2-Methyl-1,3-dioxan-2-yl)ethanolYield 49%

Procedure

The same procedure as in the steps (8a) and (8b) of Example 8, was repeated using ethyl acetoacetate to obtain the title compound (5.4 g, total yield: 49%) as a light yellow oil.

Sources & evidence

ORD record: ord-f1c96fd3e135466e981fd004cf3af29f
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07425634B2

Reaction notes

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