p-Bromobenzenesulfonyl chloride → 4-(4-BOC-piperazinosulfonyl)bromobenzene

HRID 317368Notes

Reaction equation

HRID 317368 reaction equation
[Br:21][c:22]1[cH:23][cH:24][c:25]([S:28](=[O:29])(=[O:30])[Cl:31])[cH:26][cH:27]1.[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]1.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][N:18]([S:28]([c:25]2[cH:24][cH:23][c:22]([Br:21])[cH:27][cH:26]2)(=[O:29])=[O:30])[CH2:19][CH2:20]1

Participants

5

Reactant 4

HCID 7396p-Bromobenzenesulfonyl chlorideHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 166655764-(4-BOC-piperazinosulfonyl)bromobenzene

Sources & evidence

ORD record
ord-72b4ab3d32f94caeb6cccd348c295513
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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