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HRID31764

反应详情

EQUATION

反应方程式

HRID 31764 的结构方程式

REACTANTS

反应物

3
结构：O=C1NC(=O)c2ccccc21
HCID6809

Phthalimide

C8H5NO2

结构：O=C([O-])[O-].[Cs+].[Cs+]
HCID10796

Cesium carbonate

CCs2O3

结构：O=C(CCl)c1ccc(Cl)cc1Cl
HCID20250

2,2',4'-Trichloroacetophenone

C8H5Cl3O

PRODUCTS

生成物

1
结构：O=C(CN1C(=O)c2ccccc2C1=O)c1ccc(Cl)cc1Cl
HCID736778

2-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione

C16H9Cl2NO3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

2 次

PROCEDURE

实验过程

1 mmol of 2,4-dichlorophenacyl chloride in DMF was added drop wise to 2 mmol of phthalimide and 2 mmol of Cs2CO3 in DMF at room temperature for fourteen hours and then purified by trituration with diethyl ether to obtain 2-[2-(2,4-dichlorophenyl)-2-oxoethyl]isoindoline-1,3-dione.

WORKUP

后处理

  1. custompurified by trituration with diethyl ether