Tetrahydrofuran → 1-(tert-Butoxycarbonyl)-4-(2-fluorobenzyl)piperidine-4-carboxylic acid
Reaction equation
[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][CH:19]([C:22](=[O:23])[OH:24])[CH2:20][CH2:21]1.[CH:1]([N-:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[F:25][c:26]1[c:27]([CH2:28][Br:29])[cH:30][cH:31][cH:32][cH:33]1.[Li+:8].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][C:19]([C:22](=[O:23])[OH:24])([CH2:28][c:27]2[c:26]([F:25])[cH:33][cH:32][cH:31][cH:30]2)[CH2:20][CH2:21]1Participants
6
Sources & evidence
- ORD record
- ord-d497eee2b82c405a81d20af4de0d7580
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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