1,2-Dichloroethane → 3-{4-[(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-butyl}-[1,3]oxazinan-2-one

HRID 317913Notes

Reaction equation

HRID 317913 reaction equation
[C:38]([O:39][BH-:40]([O:41][C:42](=[O:43])[CH3:44])[O:45][C:46](=[O:47])[CH3:48])(=[O:49])[CH3:50].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[CH2:10][CH:9]([NH:13][CH2:14][CH2:15][CH3:16])[CH2:8][CH2:7]2.[CH:29]([N:30]([CH:31]([CH3:32])[CH3:33])[CH2:34][CH3:35])([CH3:36])[CH3:37].[Cl:52][CH2:53][CH2:54][Cl:55].[Na+:51].[O:17]=[C:18]1[O:19][CH2:20][CH2:21][CH2:22][N:23]1[CH2:24][CH2:25][CH2:26][CH:27]=[O:28]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[CH2:10][CH:9]([N:13]([CH2:14][CH2:15][CH3:16])[CH2:27][CH2:26][CH2:25][CH2:24][N:23]1[C:18](=[O:17])[O:19][CH2:20][CH2:21][CH2:22]1)[CH2:8][CH2:7]2

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 923Sodium ionHCID 81531DiisopropylethylamineHCID 2724942TriacetoxyborohydrideHCID 100821727-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amineHCID 159226964-(2-Oxo-[1,3]oxazinan-3-yl)butyraldehyde

Product 1

HCID 159226973-{4-[(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-butyl}-[1,3]oxazinan-2-one

Sources & evidence

ORD record
ord-93c2b426c0374bbcb8552efe30853cd7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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