Dichloromethane → N-[4-[5-chloro-2-(2-hydroxypropan-2-yl)benzimidazol-1-yl]cyclohexyl]-N-[(5-cyano-2,3-dihydro-1H-inden-2-yl)methyl]acetamide
Reaction equation
[CH2:45]([Cl:46])[Cl:47].[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:41][C:42]([Cl:43])=[O:44].[CH3:48][N:49]([CH3:50])[c:51]1[cH:52][cH:53][n:54][cH:55][cH:56]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:13]3[CH2:14][CH2:15][CH:16]([NH:19][CH2:20][CH:21]4[CH2:22][c:23]5[cH:24][cH:25][c:26]([C:30]#[N:31])[cH:27][c:28]5[CH2:29]4)[CH2:17][CH2:18]3)[c:7]([C:9]([CH3:10])([CH3:11])[OH:12])[n:8]2)[cH:32][cH:33]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH:13]3[CH2:14][CH2:15][CH:16]([N:19]([CH2:20][CH:21]4[CH2:22][c:23]5[cH:24][cH:25][c:26]([C:30]#[N:31])[cH:27][c:28]5[CH2:29]4)[C:42]([CH3:41])=[O:44])[CH2:17][CH2:18]3)[c:7]([C:9]([CH3:10])([CH3:11])[OH:12])[n:8]2)[cH:32][cH:33]1Participants
6
Sources & evidence
- ORD record
- ord-179de7c33e6f42d0b6e94596eec1d685
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…