Water → 3-Amino-6-(4-(3-hydroxypropyl)phenyl)-N-(pyridin-3-yl)pyrazine-2-carboxamide
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[FH:39].[NH2:1][c:2]1[c:3]([C:25](=[O:26])[NH:27][c:28]2[cH:29][n:30][cH:31][cH:32][cH:33]2)[n:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][CH2:15][CH2:16][O:17][Si:18]([C:19]([CH3:20])([CH3:21])[CH3:22])([CH3:23])[CH3:24])[cH:12][cH:13]2)[cH:6][n:7]1.[OH2:40]>>[NH2:1][c:2]1[c:3]([C:25](=[O:26])[NH:27][c:28]2[cH:29][n:30][cH:31][cH:32][cH:33]2)[n:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][CH2:15][CH2:16][OH:17])[cH:12][cH:13]2)[cH:6][n:7]1Participants
5
Sources & evidence
- ORD record
- ord-59daf43f73d948958f9e72d5c3035917
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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