Bicarbonate Ion → N-(2-chloro-4-(3-(2-methyl-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)acetamide
Reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:36][Si:37]([NH:38][Si:39]([CH3:40])([CH3:41])[CH3:42])([CH3:43])[CH3:44].[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[n:10][cH:11][n:12]([CH:18]3[O:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[c:13]2[n:14][c:15]([CH3:17])[n:16]1.[Li:45].[NH2:24][c:25]1[cH:26][c:27]([Cl:35])[c:28]([NH:31][C:32]([CH3:33])=[O:34])[cH:29][cH:30]1.[Na+:55].[O-:51][C:52]([OH:53])=[O:54]>>[c:2]1([NH:24][c:25]2[cH:26][c:27]([Cl:35])[c:28]([NH:31][C:32]([CH3:33])=[O:34])[cH:29][cH:30]2)[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[n:10][cH:11][n:12]([CH:18]3[O:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[c:13]2[n:14][c:15]([CH3:17])[n:16]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-3cc95c7ee2244fa48fca163c9df7b5e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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