Hydrochloric Acid → (1H-Indol-5-yl)-[6-(4-{[(thiophen-2-ylmethyl)-amino]-methyl}-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-amine

HRID 318983Notes

Reaction equation

HRID 318983 reaction equation
[CH3:35][S:36]([OH:37])(=[O:38])=[O:39].[ClH:40].[nH:8]1[cH:9][cH:10][c:11]2[cH:12][c:13]([NH:17][c:18]3[c:19]4[c:20]([n:21][cH:22][n:23]3)[cH:24][c:25](-[c:27]3[cH:28][cH:29][c:30]([CH:31]=[O:32])[cH:33][cH:34]3)[s:26]4)[cH:14][cH:15][c:16]12.[s:1]1[c:2]([CH2:6][NH2:7])[cH:3][cH:4][cH:5]1>>[s:1]1[c:2]([CH2:6][NH:7][CH2:31][c:30]2[cH:29][cH:28][c:27](-[c:25]3[cH:24][c:20]4[c:19]([c:18]([NH:17][c:13]5[cH:12][c:11]6[cH:10][cH:9][nH:8][c:16]6[cH:15][cH:14]5)[n:23][cH:22][n:21]4)[s:26]3)[cH:34][cH:33]2)[cH:3][cH:4][cH:5]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6395Methanesulfonic AcidHCID 34005(2-Thienylmethyl)amineHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 18383061(1H-Indol-5-yl)-[6-(4-{[(thiophen-2-ylmethyl)-amino]-methyl}-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-amine

Sources & evidence

ORD record
ord-740c5b0b19cb4ea7b22161172622bd6c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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