Ammonium → 1-Methyl-1-phenyl-2-benzyl-1,2,3,4-tetrahydroisoquinoline

HRID 319280Notes

Reaction equation

HRID 319280 reaction equation
[Br-:1].[Br-:25].[CH3:26][Mg+:27].[Cl-:28].[NH4+:29].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1.[OH2:35].[c:2]1([C:8]2=[N+:9]([CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH2:10][CH2:11][c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]32)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([C:8]2([CH3:26])[N:9]([CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH2:10][CH2:11][c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]32)[cH:3][cH:4][cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 259Bromide ion2×HCID 312ChlorideHCID 962WaterHCID 8028TetrahydrofuranHCID 108096392-Benzyl-1-phenyl-3,4-dihydroisoquinolin-2-iumHCID 178477777HCID 178477777, compound

Product 1

HCID 106389451-Methyl-1-phenyl-2-benzyl-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-870e5c2abaaa4c578f9df8ab49243f87
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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