N-methyl-2-pyrrolidone → 6-Cyano-pyrido[3,4-d]pyrimidin-4-one

HRID 320355Notes

Reaction equation

HRID 320355 reaction equation
[CH3:16][N:17]1[CH2:18][CH2:19][CH2:20][C:21]1=[O:22].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][nH:8][c:9]2=[O:10])[cH:11][n:12]1.[Cu:23][I:24].[K:13][C:14]#[N:15]>>[c:2]1([C:14]#[N:15])[cH:3][c:4]2[c:5]([n:6][cH:7][nH:8][c:9]2=[O:10])[cH:11][n:12]1

Participants

5

Reactant 4

HCID 13387N-methyl-2-pyrrolidoneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 1354805256-chloro-3H,4H-pyrido[3,4-d]pyrimidin-4-oneHCID 178511842HCID 178511842, compound

Product 1

HCID 1358174456-Cyano-pyrido[3,4-d]pyrimidin-4-one

Sources & evidence

ORD record
ord-fda1b044624942c9a1c3d7220b33b4f6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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