Chloride → 2-(2,2,2-Trifluoroethyl)-4-benzyl-5-[4-(methylsulfonyl)phenyl]-3(2H)-pyridazinone
Reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[Mg+:9].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[Cl-:1].[F:10][C:11]([CH2:12][n:13]1[n:14][cH:15][c:16](-[c:21]2[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]2)[c:17]([Cl:20])[c:18]1=[O:19])([F:31])[F:32]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[c:17]1[c:16](-[c:21]2[cH:22][cH:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]2)[cH:15][n:14][n:13]([CH2:12][C:11]([F:10])([F:31])[F:32])[c:18]1=[O:19]Participants
5
Sources & evidence
- ORD record
- ord-577b3d8ca94f496fbae38f0a6100e7bd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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