Bicarbonate Ion → N-Cyclopropylmethyl-N-[7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-(methoxymethyl)pyrazolo[1,5-a]pyridin-3-yl]-N-tetrahydro-3-furanylmethylamine

HRID 320523Notes

Reaction equation

HRID 320523 reaction equation
[BH4-:43].[C:45](=[O:46])([OH:47])[O-:48].[CH3:55][CH2:56][O:57][C:58](=[O:59])[CH3:60].[CH:1]1([CH2:4][NH:5][c:6]2[c:7]([CH2:28][O:29][CH3:30])[n:8][n:9]3[c:10]2[cH:11][cH:12][cH:13][c:14]3-[c:15]2[c:16]([O:26][CH3:27])[cH:17][c:18]([CH2:23][O:24][CH3:25])[cH:19][c:20]2[O:21][CH3:22])[CH2:2][CH2:3]1.[Na+:44].[Na+:49].[O:31]1[CH2:32][CH:33]([CH:36]=[O:37])[CH2:34][CH2:35]1.[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1.[OH2:61].[S:38](=[O:39])(=[O:40])([OH:41])[OH:42]>>[CH:1]1([CH2:4][N:5]([c:6]2[c:7]([CH2:28][O:29][CH3:30])[n:8][n:9]3[c:10]2[cH:11][cH:12][cH:13][c:14]3-[c:15]2[c:16]([O:26][CH3:27])[cH:17][c:18]([CH2:23][O:24][CH3:25])[cH:19][c:20]2[O:21][CH3:22])[CH2:36][CH:33]2[CH2:32][O:31][CH2:35][CH2:34]2)[CH2:2][CH2:3]1

Participants

10

Reactant 9

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 962WaterHCID 1118Sulfuric AcidHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 28123BorohydrideHCID 1575683-Furancarboxaldehyde, tetrahydro-HCID 21084165N-Cyclopropylmethyl-N-[7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-(methoxymethyl)pyrazolo[1,5-a]pyridin-3-yl]amine

Product 1

HCID 21084167N-Cyclopropylmethyl-N-[7-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-2-(methoxymethyl)pyrazolo[1,5-a]pyridin-3-yl]-N-tetrahydro-3-furanylmethylamine

Sources & evidence

ORD record
ord-4d9190f1f25547a2b88766eb356d600c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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