Tetrahydrofuran → 1-Benzyl-4-phenyl-3-pyrrolidinemethanol

HRID 321102Notes

Reaction equation

HRID 321102 reaction equation
[Al+3:35].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([C:19](=[O:20])[N:21]2[CH:22]([CH2:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[CH2:30][O:31][C:32]2=[O:33])[CH:11]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:12]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[H-:34].[H-:37].[H-:38].[H-:39].[Li+:36]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH2:19][OH:20])[CH:11]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:12]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 219127084-Benzyl-3-(1-benzyl-4-phenylpyrrolidine-3-carbonyl)-1,3-oxazolidin-2-one

Product 1

HCID 219127561-Benzyl-4-phenyl-3-pyrrolidinemethanol

Sources & evidence

ORD record
ord-3d94bcde418e434ca6f1258b82fe400c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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