Chloroacetyl chloride → N-[4-amino-5-(5-iodo-2-isopropyl-4-methoxy-phenoxy)-pyrimidin-2-yl]-2-chloro-acetamide
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[Cl:29][CH2:30][C:31](=[O:32])[Cl:33].[I:1][c:2]1[c:3]([O:20][CH3:21])[cH:4][c:5]([CH:17]([CH3:18])[CH3:19])[c:6]([O:7][c:8]2[c:9]([NH2:15])[n:10][c:11]([NH2:14])[n:12][cH:13]2)[cH:16]1>>[I:1][c:2]1[c:3]([O:20][CH3:21])[cH:4][c:5]([CH:17]([CH3:18])[CH3:19])[c:6]([O:7][c:8]2[c:9]([NH2:15])[n:10][c:11]([NH:14][C:31]([CH2:30][Cl:29])=[O:32])[n:12][cH:13]2)[cH:16]1Participants
5
Sources & evidence
- ORD record
- ord-543f856a65a34b03972596cdff20786c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…