Methane → 4-(Azetidin-1-ylmethyl)piperidine-1-carboxylic acid [4-(4-amino-2-fluorophenoxy)pyridin-2-yl]amide
Reaction equation
[C:39].[CH3:37][OH:38].[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]([NH:11][C:12](=[O:13])[N:14]3[CH2:15][CH2:16][CH:17]([CH2:20][N:21]4[CH2:22][CH2:23][CH2:24]4)[CH2:18][CH2:19]3)[n:8][cH:9][cH:10]2)[cH:25][cH:26][c:27]([N+:29]([O-:30])=[O:31])[cH:28]1.[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[Pd:40]>>[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]([NH:11][C:12](=[O:13])[N:14]3[CH2:15][CH2:16][CH:17]([CH2:20][N:21]4[CH2:22][CH2:23][CH2:24]4)[CH2:18][CH2:19]3)[n:8][cH:9][cH:10]2)[cH:25][cH:26][c:27]([NH2:29])[cH:28]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c0ca28354f9647e5872cb846b318d9e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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