Benzaldehyde → HCID 77793913, compound

HRID 321986Notes

Reaction equation

HRID 321986 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:20][NH2:21])[CH:5]=[C:6]([Cl:19])[C:7]=1[CH:8]([C:17]#[N:18])[C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[C:11]([Cl:16])[CH:10]=1.[CH:22](=O)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.[CH2:30]([O:32][C:33](=[O:35])[CH3:34])[CH3:31]>>[CH2:30]([O:32][C:33](=[O:35])[CH3:34])[CH3:31].[Cl:1][C:2]1[CH:3]=[C:4]([NH:20][N:21]=[CH:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:5]=[C:6]([Cl:19])[C:7]=1[CH:8]([C:17]#[N:18])[C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[C:11]([Cl:16])[CH:10]=1

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 8857Ethyl AcetateHCID 220085563,5-Dichloro-4-(3,4-dichloro-alpha-cyanobenzyl)phenylhydrazine

Product 1

HCID 77793913HCID 77793913, compoundYield 68%

Procedure

In 50 ml of acetic acid ethyl ester was dissolved 3.0 g of 3,5-dichloro-4-(3,4-dichloro-α-cyanobenzyl)phenylhydrazine. To the solution was added equimol. of benzaldehyde, and the mixture was stirred for 3 hours at room temperature. The reaction mixture was dried over anhydrous magnesium sulfate, which was then concentrated to afford the titled compound in a yield of 68%, m.p.75-90° C.

Workup

  1. additionTo the solution was added equimol
  2. dry with materialThe reaction mixture was dried over anhydrous magnesium sulfate, which
  3. concentrationwas then concentrated

Sources & evidence

ORD record
ord-ae59b0bc5268499fb28529708310a220
Source dataset
uspto-grants-2001_04
Patent number
US06211178B1

Reaction notes

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