反应详情

温度

75 °C

200.0 mg (0.92 mmol) of trans-4-trifluoromethylcinnamic acid were treated with 200 μl of thionyl chloride. After addition of 2 drops of DMF, the reaction solution obtained was stirred at 75° C. for 3 h. It was then concentrated to dryness, and the residue was taken up in toluene 2× and concentrated to dryness again. Drying in a high vacuum yielded 237.0 mg of the title compound as a slightly yellow, amorphous powder.

1. customthe reaction solution obtained
2. concentrationIt was then concentrated to dryness
3. concentrationconcentrated to dryness again
4. customDrying in a high vacuum