Hydrogen Bromide → HCID 131722477, compound

HRID 322786Notes

Reaction equation

HRID 322786 reaction equation
[CH:1]([NH2:3])=[S:2].C(OC([N:11]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:12][C:13]([OH:15])=[O:14])=O)(C)(C)C.[BrH:22]>C(O)(=O)C>[BrH:22].[CH:1]([NH2:3])=[S:2].[C:16]1([NH:11][CH2:12][C:13]([OH:15])=[O:14])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 131722478HCID 131722478, compound

Product 1

HCID 131722477HCID 131722477, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 364 mg of t-butoxycarbonyl phenylglycine thiocarboxamide in 4 mL 30% HBr in acetic acid was stirred for 1 hour. The volitile materials were removed under reduced pressure and the crude phenylglycine thiocarboxamide hydrobromide was obtained as a pale solid. The material was utilized without further purification.

Workup

  1. customThe volitile materials were removed under reduced pressure

Sources & evidence

ORD record
ord-567bca1b16cc4c98ba92fd3ac8e3d3a5
Source dataset
uspto-grants-2001_04
Patent number
US06211235B1

Reaction notes

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