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HRID32397

反应详情

EQUATION

反应方程式

HRID 32397 的结构方程式

REACTANTS

反应物

3
结构：NO
HCID787

Hydroxylamine

H3NO

结构：CC(C)(C)OC(=O)N1CCC(COS(C)(=O)=O)CC1
HCID2765838

tert-Butyl 4-{[(methanesulfonyl)oxy]methyl}piperidine-1-carboxylate

C12H23NO5S

结构：CCCC[C@@H](N)CO
HCID6994402

未命名化合物

PRODUCTS

生成物

1
结构：CCCC[C@@H](N)COCC1CCN(C(=O)OC(C)(C)C)CC1
HCID69309660

未命名化合物

PROCEDURE

实验过程

Using amino alcohol alkylation method A, but adding 1.1 equivalents of 4-methanesulfonyloxymethyl-piperidine-1-carboxylic acid tert-butyl ester instead of 1 equivalent, (R)-norleucinol (400 mg, 3.4 mmol) afforded, after purification (SiO2: 7:3:1 hexane:EtOAc:isopropyl amine), 195 mg (18%) of the title compound.

WORKUP

后处理

  1. customafforded
  2. customafter purification (SiO2: 7:3:1 hexane:EtOAc:isopropyl amine), 195 mg (18%) of the title compound