Hydrochloric Acid → HCID 15524306, compound

HRID 324350Notes

Reaction equation

HRID 324350 reaction equation
Cl.[Cl:2][C:3]1[CH:4]=[C:5]([CH:31]=[CH:32][C:33]=1[O:34][CH3:35])[CH2:6][NH:7][C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]([C:18]#[N:19])[CH:16]=2)[C:11](=[O:20])[N:10]([CH2:21][CH2:22][CH2:23][O:24]C2CCCCO2)[N:9]=1>CO>[Cl:2][C:3]1[CH:4]=[C:5]([CH:31]=[CH:32][C:33]=1[O:34][CH3:35])[CH2:6][NH:7][C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]([C:18]#[N:19])[CH:16]=2)[C:11](=[O:20])[N:10]([CH2:21][CH2:22][CH2:23][OH:24])[N:9]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15524305HCID 15524305, compound

Product 1

HCID 15524306HCID 15524306, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Methanol (20 ml) and 1N hydrochloric acid (2 ml) were added to the 4-(3-chloro-4-methoxybenzyl)amino-6-cyano-2-[3-(tetrahydropyran-2-yloxy)propyl]-1(2H)-phthalazinone (0.20 g) prepared in Example 24. The obtained mixture was stirred at room temperature for 3 hours.

Sources & evidence

ORD record
ord-9dcacfdca6934eeaaa6d9e320ad64be5
Source dataset
uspto-grants-2001_04
Patent number
US06218392B1

Reaction notes

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