反应详情

2-methyl-2-adamantanol (33 g, 0.2 mol) and triethylamine (0.22 mol) were dissolved in 300 ml of THF and then acryloyl chloride (19 g, 0.21 mol) was added slowly thereto using a dropping funnel. Then, the reaction was stirred at room temperature for about 12 hours. After completion of the reaction, excess THF was removed using a rotary evaporator and then the resultant product was poured into water. Then, the resultant product was neutralized with dilute sulfuric acid and extracted using diethyl ether and was then dried over magnesium sulfate. The diethyl ether removed crude product was vacuum-distilled to yield the desired product (yield: 80%).

1. customwas removed
2. customa rotary evaporator
3. additionthe resultant product was poured into water
4. extractionextracted
5. dry with materialwas then dried over magnesium sulfate
6. customThe diethyl ether removed crude product
7. distillationwas vacuum-distilled