反应详情

To a solution of 4-pentyl-3-cyclohexen-1-methanol (3.0 g) in pyridine (3.3 ml) at 0° C. was added p-toluenesulfonyl chloride (3.3 g). The reaction was stirred in an ice bath for 2 hours, and then stored at -20 ° C. for a further 16 hours. The reaction mixture was then poured into 2 M HCl (75 ml) and extracted with ethyl acetate. The combined organic layers were extracted with saturated sodium chloride and dried over sodium sulfate. The solvent was removed in vacuo to produce 4-pentyl-3-cyclohexen-1-methanol toluenesulfonate.

1. waitstored at -20 ° C. for a further 16 hours
2. extractionextracted with ethyl acetate
3. extractionThe combined organic layers were extracted with saturated sodium chloride
4. dry with materialdried over sodium sulfate
5. customThe solvent was removed in vacuo