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HRID326983

反应详情

EQUATION

反应方程式

HRID 326983 的结构方程式

REACTANTS

反应物

3
结构：C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43CO)[C@@H]1CC[C@@H]2O
HCID150968

19-Hydroxytestosterone

C19H28O3

结构：C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43CO)[C@@H]1CCC2=O
HCID252379

未命名化合物

结构：[BH4-].[K+]
HCID4192641

Potassium tetrahydroborate

H4BK

PRODUCTS

生成物

1
结构：C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43CO)[C@@H]1CCC2O
HCID22849351

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Also known as 19-Hydroxytestosterone, this compound is commercially available from Steraloids, Inc. Alternatively, 19-hydroxyandrost-4-en-3,17-dione (11) is treated with potassium borohydride (KBH4, a) in ethanol at -10° to 0° C. Aqueous work up is followed by extraction and purification to yield 19-hydroxytestosterone (12).

WORKUP

后处理

  1. customat -10° to 0° C
  2. extractionAqueous work up is followed by extraction and purification