Triethylamine → HCID 21201151, compound

HRID 327754Notes

Reaction equation

HRID 327754 reaction equation
[O:1]=[C:2]([NH:6][C:7](=[O:16])[C:8]([NH:10][C:11](=[O:15])[CH2:12][CH2:13]Cl)=[O:9])[CH2:3][CH2:4]Cl.C(N(CC)CC)C>C(Cl)Cl>[O:15]=[C:11]([NH:10][C:8](=[O:9])[C:7]([NH:6][C:2](=[O:1])[CH:3]=[CH2:4])=[O:16])[CH:12]=[CH2:13]

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 19733575HCID 19733575, compound

Product 1

HCID 21201151HCID 21201151, compoundYield 4.6%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a suspension of N,N'-bis(1-oxo-3-chloropropyl)-ethanediamide (3.0 g; 11 mmol) in methylene chloride (40 ml), triethylamine (2.82 g; 28 mmol) was added, and the resultant mixture was stirred at room temperature for 2 hours. The precipitated solid was collected and washed with water to give N,N'-bis(1-oxo-2-propenyl)ethanediamide (0.1 g). Yield, 4.6%.

Workup

  1. additionwas added
  2. customThe precipitated solid was collected
  3. washwashed with water

Sources & evidence

ORD record
ord-aae568050d2e423eaa76beb26b99f99f
Source dataset
uspto-grants-1993_12
Patent number
US05274062

Reaction notes

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