Phosphorus oxychloride → 2-Chloro-5-(methylthio)-1,3-dinitrobenzene

HRID 328463Notes

Reaction equation

HRID 328463 reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[C:6](O)=[C:5]([N+:13]([O-:15])=[O:14])[CH:4]=1.P(Cl)(Cl)([Cl:18])=O>CN(C)C=O>[Cl:18][C:6]1[C:7]([N+:9]([O-:11])=[O:10])=[CH:8][C:3]([S:2][CH3:1])=[CH:4][C:5]=1[N+:13]([O-:15])=[O:14]

Participants

4

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 21442503HCID 21442503, compound

Product 1

HCID 214425072-Chloro-5-(methylthio)-1,3-dinitrobenzene

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 4-(methylthio)-2,6-dinitrophenol (1 g.), phosphorus oxychloride (7.5 ml.), and dimethylformamide (1 ml.) is heated at 90°-100° C. for four hours. The cooled reaction mixture is poured into ice-water. The resulting product is collected by filtration.

Workup

  1. temperatureis heated at 90°-100° C. for four hours
  2. customThe cooled reaction mixture
  3. filtrationThe resulting product is collected by filtration

Sources & evidence

ORD record
ord-06eda12b8ab249d1a1886d0b9415fd24
Source dataset
uspto-grants-1977_04
Patent number
US04017538

Reaction notes

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