Iodoethane → HCID 21440143, compound

HRID 328953Notes

Reaction equation

[C:1]([C:9]1C([N+]([O-])=O)=CC(C(OCC)=O)=CC=1O)(=O)[C:2]1C=CC=C[CH:3]=1.C(I)C.[Cl:27][C:28]1[CH:50]=[CH:49][C:31]([C:32]([C:34]2[C:44]([N+:45]([O-:47])=[O:46])=[CH:43][C:37]([C:38]([O:40]CC)=[O:39])=[CH:36][C:35]=2[OH:48])=[O:33])=[CH:30][CH:29]=1.C(I)CCC>>[CH2:9]([O:48][C:35]1[CH:36]=[C:37]([CH:43]=[C:44]([N+:45]([O-:47])=[O:46])[C:34]=1[C:32](=[O:33])[C:31]1[CH:49]=[CH:50][C:28]([Cl:27])=[CH:29][CH:30]=1)[C:38]([OH:40])=[O:39])[CH2:1][CH2:2][CH3:3]

Participants

Reactant 4

HCID 6340Iodoethane

HCID 10962Butyl iodide

HCID 21440132HCID 21440132, compound

HCID 21440153HCID 21440153, compound

Product 1

HCID 21440143HCID 21440143, compound

Procedure

By replacing in Example 6, step B, ethyl 4-benzoyl-3-hydroxy-5-nitrobenzoate and ethyl iodide with equimolar amounts of ethyl 4-(4'-chlorobenzoyl)-3-hydroxy-5-nitrobenzoate and n-butyl iodide respectively and following the procedure described, 3-n-butoxy-4-(4'-chlorobenzoyl)-5-nitrobenzoic acid is obtained with a melting point of 180°-182° C.

Sources & evidence

ORD record: ord-886b072d131e4478bcebd335eb26870d
Source dataset: uspto-grants-1977_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04018794

Reaction notes

Loading…