Hydrochloric Acid → HCID 19872053, compound

HRID 329377Notes

Reaction equation

HRID 329377 reaction equation
C([NH:4][C:5]1[CH:27]=[CH:26][C:8]([O:9][CH2:10][CH2:11][N:12]2[CH2:18][CH2:17][C:16]3[CH:19]=[CH:20][C:21]([N+:23]([O-:25])=[O:24])=[CH:22][C:15]=3[CH2:14][CH2:13]2)=[CH:7][C:6]=1[CH3:28])(=O)C.[ClH:29]>>[ClH:29].[ClH:29].[NH2:4][C:5]1[CH:27]=[CH:26][C:8]([O:9][CH2:10][CH2:11][N:12]2[CH2:18][CH2:17][C:16]3[CH:19]=[CH:20][C:21]([N+:23]([O-:25])=[O:24])=[CH:22][C:15]=3[CH2:14][CH2:13]2)=[CH:7][C:6]=1[CH3:28]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 19872055HCID 19872055, compound

Product 1

HCID 19872053HCID 19872053, compound

Procedure

3-[2-(4-Acetylamino-3-methylphenoxy)ethyl]-7-nitro-1,2,4,5-tetrahydro-3H-3-benzazepine (1 g) was stirred in 6M hydrochloric acid (20 ml) at 90° for 18 hours. After cooling, the precipitate was collected by filtration and recrystallised from ethanol to give the title compound, yield 0.65 g, m.p. 253°-256°.

Workup

  1. temperatureAfter cooling
  2. filtrationthe precipitate was collected by filtration
  3. customrecrystallised from ethanol

Sources & evidence

ORD record
ord-074708e098b142c7a90544498a37bac1
Source dataset
uspto-grants-1990_01
Patent number
US04891372

Reaction notes

Loading…