反应详情

A mixture of 11.9 ml of benzyl bromide in 100 ml of ether was added dropwise to a solution of 29.6 ml of piperidine in 100 ml of ether. This mixture was stirred overnight, then filtered. The organic layer was washed with water, then dried and concentrated to an oil. The oil was distilled through a Kugelrohr and the fraction boiling at 75°-85° C., 1.55 mm collected, giving 16.77 g of 1-(phenylmethyl)piperidine as an oil.

1. filtrationfiltered
2. washThe organic layer was washed with water
3. customdried
4. concentrationconcentrated to an oil
5. distillationThe oil was distilled through a Kugelrohr
6. customthe fraction boiling at 75°-85° C., 1.55 mm collected