反应详情

A solution of phenyl 4-nitrobenzenemethanesulphonate (1.6 g) in ethyl acetate (200 ml) and concentrated hydrochloric acid (1 ml) was hydrogenated over prereduced 5% palladium oxide on charcoal (50% aqueous paste 0.4 g) in ethanol (10 ml) at atmospheric pressure and temperature. The catalyst was filtered off and the filtrate concentrated to give the title compound as a solid (1.55 g). A small sample (0.2 g) was crystallized from isopropyl acetate (10 ml) and a few drops of methanol to give analytically pure material (70 mg) m.p. 147°-148°.

1. filtrationThe catalyst was filtered off
2. concentrationthe filtrate concentrated