Hydrochloric Acid → HCID 178511347, compound

HRID 330215Notes

Reaction equation

HRID 330215 reaction equation
[P:1]([OH:4])([OH:3])[OH:2].[NH2:5][CH2:6][CH2:7][NH:8][CH2:9][CH2:10][NH:11][CH2:12][CH2:13][NH2:14].Cl.C=O>>[PH:1](=[O:2])([OH:4])[OH:3].[NH2:5][CH2:6][CH2:7][NH:8][CH2:9][CH2:10][NH:11][CH2:12][CH2:13][NH2:14]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 712Formaldehyde2×HCID 5565TriethylenetetramineHCID 107909Phosphorous acid

Product 1

HCID 178511347HCID 178511347, compound

Procedure

To a 1 liter 5 neck flask fitted with a reflux condenser and dropping funnel is added 234.3 grams (2 mole) 70% phosphorous acid. Triethylenetetramine, 146 grams (1 mole) is then added dropwise while stirring, followed by 146 grams (4 moles) anhydrous HCl. The mixture is then heated to reflux and 162.2 grams (2 moles) 37% aqueous formaldehyde is added dropwise over 1 hour. Reflux is maintained for 2 hours after formaldehyde addition is complete, after which the reaction mixture containing the amino methylene phosphonic acid product is cooled and bottled.

Workup

  1. temperatureThe mixture is then heated
  2. temperatureto reflux
  3. temperatureReflux
  4. temperatureis maintained for 2 hours
  5. temperatureis cooled

Sources & evidence

ORD record
ord-8b1c5df5c4e3433c8fc392a53c1c13f8
Source dataset
uspto-grants-1990_01
Patent number
US04895600

Reaction notes

Loading…