反应详情

A mixture of 10 mmol 2,6-dichlorobenzothiazole, 12.3 mmol of piperazine and 20 mmol of potassium carbonate in 50 ml of acetonitrile was refluxed for 3 hours. The reaction mixture was concentrated and treated with 25 ml of water. Extraction with ethyl acetate, drying over magnesium sulfate, and evaporation of the solvent yielded the title compound as a colorless solid.

1. temperaturewas refluxed for 3 hours
2. concentrationThe reaction mixture was concentrated
3. additiontreated with 25 ml of water
4. extractionExtraction with ethyl acetate
5. dry with materialdrying over magnesium sulfate, and evaporation of the solvent