Methyl iodide → 1-(2-Bromo-4-cyanophenyl)-3-methylimidazolium iodide

HRID 333023Notes

Reaction equation

HRID 333023 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([C:8]#[N:9])[CH:5]=[CH:4][C:3]=1[N:10]1[CH:14]=[CH:13][N:12]=[CH:11]1.[CH3:15][I:16]>O1CCCC1>[I-:16].[Br:1][C:2]1[CH:7]=[C:6]([C:8]#[N:9])[CH:5]=[CH:4][C:3]=1[N+:10]1[CH:14]=[CH:13][N:12]([CH3:15])[CH:11]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 688544441-(2-Bromo-4-cyanophenyl)imidazole

Product 1

HCID 1784806631-(2-Bromo-4-cyanophenyl)-3-methylimidazolium iodide

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

1-(2-Bromo-4-cyanophenyl)imidazole (5.4 g, 22 mmol, 1 eq) and methyl iodide (15.4 g, 109.0 mmol, 5 eq) are dissolved in tetrahydrofuran (50 ml) and stirred at room temperature for 16 hours. The precipitate formed is filtered off and washed with ethanol.

Workup

  1. customThe precipitate formed
  2. filtrationis filtered off
  3. washwashed with ethanol

Sources & evidence

ORD record
ord-28d73abda1b7430bb1c5c08c68a27d33
Source dataset
uspto-grants-2014_11
Patent number
US08877937B2

Reaction notes

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