反应详情

Into a 0.25 L, 3-necked roundbottom flask, fitted with a magnetic stirbar, addition funnel, and reflux condenser were added 6-acetoxy-2-naphthoic acid (30.0 g, 130 mmol), THF (135 mL) and dimethylformamide (approx. 20 drops). Thionyl chloride (18.6 g, 156 mmol) was added slowly dropwise to the reaction mixture over 15 minutes. The reaction mixture was heated to reflux for 2.5 hours under nitrogen and allowed to cool to room temperature overnight.

1. customInto a 0.25 L, 3-necked roundbottom flask, fitted with a magnetic stirbar, addition funnel
2. temperaturereflux condenser
3. temperatureThe reaction mixture was heated
4. temperatureto reflux for 2.5 hours under nitrogen