反应详情

20 g (71 mmol) 7-acetyl-5-benzyloxy-3H-benzoxazol-2-one and 8 g (72 mmol) selenium dioxide are refluxed for 8 hours in the presence of activated charcoal in 100 mL dioxane and 3.1 mL water. The solid is filtered off, the solvent is distilled off and the residue is combined with 50 mL ethanol. The mixture is refluxed for 15 minutes and then filtered through activated charcoal. The solid precipitated on cooling is suction filtered after 3 hours and washed with ethanol and diethyl ether.

1. filtrationThe solid is filtered off
2. distillationthe solvent is distilled off
3. temperatureThe mixture is refluxed for 15 minutes
4. filtrationfiltered through activated charcoal
5. customThe solid precipitated
6. temperatureon cooling
7. filtrationis suction filtered after 3 hours
8. washwashed with ethanol and diethyl ether