Oxalyl chloride → HCID 86688296, compound

HRID 334074Notes

Reaction equation

HRID 334074 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[C:7]([C:9]([OH:11])=O)[CH:6]=[CH:5][CH:4]=1.C(Cl)(=O)C([Cl:15])=O>C(Cl)Cl>[CH3:1][O:2][C:3]1[N:8]=[C:7]([C:9]([Cl:15])=[O:11])[CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 5708916-Methoxypicolinic acid

Product 1

HCID 86688296HCID 86688296, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Conditions

Temperature
40 °C

Procedure

To a mixture of 5.00 g (32.7 mmol) 6-methoxy-pyridine-2-carboxylic acid in 100 mL DCM was added 40.8 mL (81.6 mmol) 2 M oxalyl chloride solution in DCM and stirred at 40° C. for 2 h. The solvent was removed by distillation.

Workup

  1. customThe solvent was removed by distillation

Sources & evidence

ORD record
ord-7a3cb02637e540c3acfd20ff7e0b5407
Source dataset
uspto-grants-2014_11
Patent number
US08883789B2

Reaction notes

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