HRID336381
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
126 mg 2-piperazin-1-yl-nicotinonitrile was added to 216 mg (3,5-Bis-(4-fluoro-phenyl)-(1,2,4)triazol-1-yl)-acetyl chloride and 150 μL triethylamine in 10 mL dichlormethane. The reaction was stirred 1 day at RT, the solvant was evaporated and the residue was purified by HPLC to give 93 mg of the desired product. (M+H)+: 486
WORKUP
后处理
- customthe solvant was evaporated
- customthe residue was purified by HPLC