HRID336676

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID31244

4-Methoxybenzaldehyde

C8H8O2

HCID20349016

2-Amino-4,6-dimethoxybenzamide

C9H12N2O3

反应SMILES：COc1cc(OC)c2c(=O)[nH]c(-c3ccccn3)nc2c1

HCID136037998

未命名化合物

PRODUCTS

产物

反应SMILES：COc1ccc(-c2nc3cc(OC)cc(OC)c3c(=O)[nH]2)cc1

HCID136037961

未命名化合物

收率 44%

PROCEDURE

实验过程

5,7-Dimethoxy-2-(4-methoxyphenyl)quinazolin-4(3H)-one was synthesized from 2-amino-4,6-dimethoxybenzamide and 4-methoxy benzaldehyde, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 5,7-Dimethoxy-2-(4-methoxyphenyl)quinazolin-4(3H)-one (106 mg, 44%) was isolated as an off-white solid. Selected data: MS (m/z): 312.99; MP 276-277° C.