Cyanuric chloride → HCID 22094203, compound

HRID 340856Notes

Reaction equation

HRID 340856 reaction equation
[N:1]1[C:8](Cl)=[N:7][C:5]([Cl:6])=[N:4][C:2]=1Cl.[CH2:10]([NH:14][CH:15]1[CH2:20][C:19]([CH3:22])([CH3:21])[N:18]([O:23][CH2:24][CH2:25][CH3:26])[C:17]([CH3:28])([CH3:27])[CH2:16]1)[CH2:11][CH2:12][CH3:13]>C1(C)C(C)=CC=CC=1.O>[CH2:10]([N:14]([CH:15]1[CH2:16][C:17]([CH3:28])([CH3:27])[N:18]([O:23][CH2:24][CH2:25][CH3:26])[C:19]([CH3:21])([CH3:22])[CH2:20]1)[C:8]1[N:1]=[C:2]([N:14]([CH2:10][CH2:11][CH2:12][CH3:13])[CH:15]2[CH2:16][C:17]([CH3:27])([CH3:28])[N:18]([O:23][CH2:24][CH2:25][CH3:26])[C:19]([CH3:22])([CH3:21])[CH2:20]2)[N:4]=[C:5]([Cl:6])[N:7]=1)[CH2:11][CH2:12][CH3:13]

Participants

5

Reactant 2

HCID 7954Cyanuric chlorideHCID 16726371HCID 16726371, compound2×

Product 1

HCID 22094203HCID 22094203, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 7237O-XyleneSolvent3×

Procedure

A four-necked round-bottom flask equipped with a mechanical stirrer, thermocouple, dropping funnel and condenser is charged with 27.3 g (0.148 mol) of cyanuric chloride and 200 mL of xylene at 0-5° C. 40 g (0.148 mol) of compound I-102 in 25 mL of xylene are slowly added over 20 minutes to this solution. After 90 minutes, further 40 g (0.148 mol) of compound I-102 in 25 mL of xylene and 25 mL of water are slowly added over 20 minutes to the system allowing the temperature to reach 45° C.

Workup

  1. customA four-necked round-bottom flask equipped with a mechanical stirrer
  2. customto reach 45° C.

Sources & evidence

ORD record
ord-ebd0ae5e86714f33bf8292ab6c09658d
Source dataset
uspto-grants-2014_11
Patent number
US08895647B2

Reaction notes

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