反应详情

To a solution of 3-bromophenol (0.865 g, 5 mmol) in MeOH (1.5 ml) was added 2-bromoethyl methyl ether (0.56 ml, 6 mmol) followed by K2CO3 (0.68 g, 5 mmol). The mixture was heated using microwave irradiation in a CEM discover microwave synthesizer (50 W) at 100° C. until the reaction was complete. The reaction was diluted with ether and filtered to remove solid which was washed with further ether. Filtrate concentrated under reduced pressure to give (0.8 g) of product.

1. temperatureThe mixture was heated
2. custommicrowave irradiation in a CEM
3. customat 100° C.
4. filtrationfiltered
5. customto remove solid which
6. washwas washed with further ether
7. concentrationFiltrate concentrated under reduced pressure