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HRID34121

反应详情

EQUATION

反应方程式

HRID 34121 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：COc1c(C(=O)NCC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)ccc2[nH]nc(/C=C/c3ccc(F)cc3)c12
HCID60034979

未命名化合物

PRODUCTS

生成物

1
结构：COc1c(C(=O)NCC(=O)N2CCNCC2)ccc2[nH]nc(/C=C/c3ccc(F)cc3)c12
HCID60034647

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

4-[2-({3-[(E)-2-(4-Fluorophenyl)-vinyl]-4-methoxy-1H-indazole-5-carbonyl}-amino)-acetyl]-piperazine-1-carboxylic acid tert-butyl ester obtained by Example 1215 was dissolved in 1 mL of dichloromethane, added with 1 mL of trifluoroacetic acid, and stirred at room temperature for 2 hours. The solvent was evaporated, followed by purification by LC-MS, to afford the title compound.

WORKUP

后处理

  1. customThe solvent was evaporated
  2. customfollowed by purification by LC-MS