反应详情

A mixture of dibromohydantoin (70 g, 0.24 mol) and AlBN (5 g) was added in portions at 150° C. to 2,6-dichloro-3-nitrotoluene (100 g, 0.48 mol) in chlorobenzene (400 ml). After 1 h, a mixture of dibromohydantoin (35 g, 0.12 mol) and AIBN (2.5 g) was again added. After a further 1.5 h, the mixture was allowed to cool and EA (500 ml) was added. This mixture was washed once each with saturated Na2SO3, Na2CO3 and NaCl solution, dried (MgSO4) and concentrated, the title compound being obtained as an amorphous powder.

1. additionwas again added
2. waitAfter a further 1.5 h
3. temperatureto cool
4. washThis mixture was washed once each with saturated Na2SO3, Na2CO3 and NaCl solution
5. dry with materialdried (MgSO4)
6. concentrationconcentrated