Hydrochloric Acid → HCID 13922800, compound

HRID 34330Notes

Reaction equation

HRID 34330 reaction equation
[Na].[O:2]=[C:3]([C:10]1[CH:15]=[CH:14][C:13]([S:16]C(=O)N(C)C)=[CH:12][CH:11]=1)[CH2:4][CH2:5][C:6]([O:8][CH3:9])=[O:7].O.Cl>CO>[O:2]=[C:3]([C:10]1[CH:11]=[CH:12][C:13]([SH:16])=[CH:14][CH:15]=1)[CH2:4][CH2:5][C:6]([O:8][CH3:9])=[O:7]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 5360545SodiumHCID 14211171HCID 14211171, compound

Product 1

HCID 13922800HCID 13922800, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Sodium (280 mg) was dissolved in anhydrous methanol (50 ml) under a N2 atmosphere. To the resulting solution there was added 5.0 g of the compound from Step 4. The mixture was stirred at room temperature overnight, then poured into a mixture containing 30 ml of water and 7 ml of concentrated HCl. The resulting yellow solid was collected by filtration, washed with water and dried in air to give the title compound, m.p. 83°-84°.

Workup

  1. additionpoured into a mixture
  2. filtrationThe resulting yellow solid was collected by filtration
  3. washwashed with water
  4. customdried in air

Sources & evidence

ORD record
ord-d5be50806472493191b512fc9a12f8b7
Source dataset
uspto-grants-1988_08
Patent number
US04761425

Reaction notes

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