反应详情

Sodium (280 mg) was dissolved in anhydrous methanol (50 ml) under a N2 atmosphere. To the resulting solution there was added 5.0 g of the compound from Step 4. The mixture was stirred at room temperature overnight, then poured into a mixture containing 30 ml of water and 7 ml of concentrated HCl. The resulting yellow solid was collected by filtration, washed with water and dried in air to give the title compound, m.p. 83°-84°.

1. additionpoured into a mixture
2. filtrationThe resulting yellow solid was collected by filtration
3. washwashed with water
4. customdried in air