Hydrochloric Acid → HCID 70059665, compound

HRID 343399Notes

Reaction equation

HRID 343399 reaction equation
[Br:1][C:2]1[CH:18]=[C:17]([Br:19])[CH:16]=[CH:15][C:3]=1[C:4]([CH:6]1[CH2:11][CH2:10][N:9](C(=O)C)[CH2:8][CH2:7]1)=[O:5].[ClH:20]>>[ClH:20].[Br:1][C:2]1[CH:18]=[C:17]([Br:19])[CH:16]=[CH:15][C:3]=1[C:4]([CH:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=[O:5]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 54281626HCID 54281626, compound

Product 1

HCID 70059665HCID 70059665, compound

Procedure

A stirred mixture of 1-[4-(2,4-dibromo-benzoyl)-piperidin-1-yl]-ethanone (11.00 g, 28.3 mmol) and aqueous 5M hydrochloric acid (60 ml) was heated under reflux under nitrogen for 7 h. The mixture was evaporated in vacuo to give the title compound as a white solid (10.8 g).

Workup

  1. temperaturewas heated
  2. temperatureunder reflux under nitrogen for 7 h
  3. customThe mixture was evaporated in vacuo

Sources & evidence

ORD record
ord-684918e6067b4a388be21aac1e94ab7d
Source dataset
uspto-grants-1999_01
Patent number
US05861414

Reaction notes

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