4-Chlorobenzyl alcohol → HCID 13654376, compound

HRID 344245Notes

Reaction equation

HRID 344245 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][OH:7])=[CH:4][CH:3]=1.[H-].[Na+].Br[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][Cl:18]>>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][O:7][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][Cl:18])=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 133974-Chlorobenzyl alcoholHCID 24758Sodium hydrideHCID 960701-Bromo-5-chloropentane

Product 1

HCID 13654376HCID 13654376, compoundYield 48.3%

Procedure

4-Chlorobenzyl alcohol (4.3 g), 60% sodium hydride (1.8 g) and 1-bromo-5-chloropentane (6.0 g) were reacted and treated in the same manner as in Example 96 to give 3.6 g of 5-(4-chlorobenzyloxy)pentyl chloride.

Workup

  1. additiontreated in the same manner as in Example 96

Sources & evidence

ORD record
ord-e13d8ca3697c4593bbe209e79280bfea
Source dataset
uspto-grants-1999_01
Patent number
US05864039

Reaction notes

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