反应详情

温度

50 °C

Potassium carbonate (5.64 g) and 1,4-dibromobutane (5.88 g) were added to a solution of thiophenol (3 g) in dimethylformamide (40 ml), and the mixture was stirred at 50° C. for 3 hr. Water was added to the reaction mixture and the mixture was extracted with ethyl acetate. The organic layer was washed with brine, dried and the solvent was evaporated under reduced pressure to give 6.67 g of 4-phenylthiobutyl bromide.

1. extractionthe mixture was extracted with ethyl acetate
2. washThe organic layer was washed with brine
3. customdried
4. customthe solvent was evaporated under reduced pressure