Methyl p-toluenesulfonate → HCID 15052211, compound

HRID 344783Notes

Reaction equation

HRID 344783 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]([OH:8])[CH2:4][CH2:3]1.[C:9]1([CH3:20])[CH:14]=[CH:13][C:12]([S:15]([O:18]C)(=[O:17])=[O:16])=[CH:11][CH:10]=1>>[C:9]1([CH3:20])[CH:10]=[CH:11][C:12]([S:15]([O-:18])(=[O:16])=[O:17])=[CH:13][CH:14]=1.[CH3:1][N+:2]1([CH3:9])[CH2:7][CH2:6][CH:5]([OH:8])[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 6645Methyl p-toluenesulfonateHCID 660484-Piperidinol, 1-methyl-

Product 1

HCID 15052211HCID 15052211, compoundYield 274.4%

Procedure

The procedures of Reference Example 1 were repeated using 1.16 g of 1-methyl-4-piperidinol and 1.18 g of methyl p-toluenesulfonate to give 2.62 g of the desired compound, m.p. 139°-140° C. (decomp.).

Sources & evidence

ORD record
ord-e660a53039cb4338b96155293d7f1db6
Source dataset
uspto-grants-1991_10
Patent number
US05053402

Reaction notes

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