Imidazole → HCID 19993596, compound

HRID 345002Notes

Reaction equation

HRID 345002 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][CH:5]=[C:4](Cl)[N:3]=1.N1C=CN=C1.[C:17]([N:24]1[CH:28]=[CH:27][N:26]=[CH:25]1)([N:19]1[CH:23]=[CH:22][N:21]=[CH:20]1)=O>[Pd]>[N:24]1([C:17]2[N:19]=[C:23]3[CH:22]=[N:21][C:20]4[N:8]=[CH:7][CH:6]=[CH:5][C:4]=4[N:3]3[CH:2]=2)[CH:28]=[CH:27][N:26]=[CH:25]1

Participants

5

Reactant 3

HCID 795ImidazoleHCID 682631,1'-CarbonyldiimidazoleHCID 852392,6-Dichloro-3-nitropyridine

Product 1

HCID 19993596HCID 19993596, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Prepare by reaction of 2,6-dichloro-3-nitropyridine with excess imidazole followed by hydrogenation with palladium on carbon and cyclization with carbonyldiimidazole to provide the title compound.

Sources & evidence

ORD record
ord-4b548bcc7b6a4029828536e670f696e0
Source dataset
uspto-grants-1991_10
Patent number
US05055465

Reaction notes

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