4-Bromobenzaldehyde → HCID 19754542, compound

HRID 346209Notes

Reaction equation

HRID 346209 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][SH:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[C:12]1[CH:19]=[CH:18][C:15]([CH:16]=[O:17])=[CH:14][CH:13]=1>>[C:1]1([CH2:7][CH2:8][CH2:9][S:10][C:12]2[CH:19]=[CH:18][C:15]([CH:16]=[O:17])=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 707414-BromobenzaldehydeHCID 905963-Phenylpropane-1-thiol

Product 1

HCID 19754542HCID 19754542, compoundYield 101.2%

Procedure

By the method of Preparation 7, 3-phenylpropyl mercaptan (41.1 g) and 4-bromobenzaldehyde (53.7 g) were converted to 70 g of present title product, isolated as an oil following chromatography on silica gel using 9:1 hexane:ethyl acetate as eluant; tlc Rf 0.4 (1:4 ethyl acetate:hexane).

Sources & evidence

ORD record
ord-23d754181d1342f6acbf75acdbbf3d71
Source dataset
uspto-grants-1991_10
Patent number
US05061717

Reaction notes

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